Debates over the philosophical foundations of statistics have a long and fascinating history; the decline of a lively exchange between philosophers of science and statisticians is relatively recent. Is there something special about 2011 (and beyond) that calls for renewed engagement in these fields? I say yes. There are some surprising, pressing, and intriguing new philosophical twists on the long-running controversies that cry out for philosophical analysis, and I hope to galvanize my co-contributors as well as the reader to take up the general cause.